Dr Karen Adelman

Harvard Medical School, USA

Dr. Karen Adelman is the Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology at Harvard Medical School, a member of the Gene Regulation Observatory at the Broad Institute, and the Ludwig Cancer Center at Harvard Medical School. Dr. Adelman has been elected to the American Academy of Arts and Sciences and EMBO, and received the NIH Directors award for scientific excellence. The Adelman lab pioneered genomic studies of RNA polymerase II (RNAPII) transcription, revealing that pausing of RNAPII in early elongation is a central regulatory step in metazoan gene expression. Ongoing work probes the interplay between transcription, RNA processing and epigenetic machineries to elucidate the determinants of mature mRNA formation in health and disease.