2018 Lorne Genome Conference

Professor Laszlo Tora

Development and stem cells

Laszlo Tora is a Research Director (equivalent of Full Professor) at CNRS (France). 

He leads his group at Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) (Illkirch), in France. His group is interested in deciphering the basic mechanisms of transcriptional regulation, by using a large variety of techniques, ranging from biochemistry, through genetics and from molecular biology to biophysics and imaging. He and his group have significantly contributed to the development of the field. They identified and characterized many subunits of the general transcription factor, TFIID and showed that functionally different TFIID complexes exist in human cells. They have also contributed to the concept showing a tight coupling between initiation of transcription and the maturation of pre-mRNAs. They discovered and characterized novel TATA binding protein (TBP)-like factors, such as TLF/TBPL1 and TBP2/TBPL2, as well as novel human histone acetyl transferase coactivator complexes, called SAGA and a ATAC, playing a role in chromatin remodeling. 

In 2001 he was elected as a member of the European Molecular Biology Organization (EMBO) and got  he silver medal, from CNRS (France). In 2005 he has received the Alexander von Humboldt Research Award​ (Germany). In 2010 he was elected as a member of the Hungarian Academy of Sciences and in 2016 as a member of Academia Europe. In 2013 he has spent a year as a visiting professor at the School of Biological Sciences, Nanyang Technological University, Singapore. In 2014 he obtained the prestigious European Research Council grant for his "Birtoaction" project.