2018 Lorne Genome Conference

Associate Professor Julie Secombe

Mechanisms of Transcriptional Regulation

Julie received her PhD from the University of Adelaide, Australia, studying the regulation of the cell cycle. Her postdoctoral training with Dr. Robert Eisenman at the Fred Hutchinson Cancer Center (Seattle, WA) centered around defining the means by which the oncoprotein Myc regulates cell growth.  Dr. Secombe started her own research group in 2009 in the Department of Genetics at Albert Einstein College of Medicine, New York. Her research focuses on defining mechanisms of transcriptional regulation, with particular emphasis on two transcriptional regulators, Myc and KDM5 (also known as Lid). Our work with Myc has revealed an exciting link to aging and the mobilization of endogenous transposons (TEs) and our investigations of KDM5 have identified novel links to neuronal development and function.